PROCESS DEVELOPMENT AND QUALITY ATTRIBUTES FOR THE FREEZE-DRYING PROCESS IN PHARMACEUTICALS, BIOPHARMACEUTICALS AND NANOMEDICINE DELIVERY: A STATE-OF-THE-ART REVIEW

Process development and quality attributes for the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanomedicine delivery: a state-of-the-art review

Abstract Background Process intensification is a major hurdle in pharmaceutical process scale-up.Solvent removal strategies have limited the effectiveness of Alarm Clock the overall stability of pharmaceutical formulations.The main aim of present review article is to focus on the use of the freeze-drying process in pharmaceuticals, biopharmaceutica

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